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Figure 1 | Reproductive Biology and Endocrinology

Figure 1

From: Expression of the G protein-coupled estrogen receptor (GPER) in endometriosis: a tissue microarray study

Figure 1

Immunoreactivity Scores. Mean Immunoreactivity Scores (IRS) and 95% confidence intervals (error bars) for the expression of the (A) cytoplasmic expression of the G protein-coupled estrogen receptor (GPER cytoplasmic), the (B) nuclear expression of the G protein-coupled estrogen receptor (GPER nuclear), the (C) estrogen receptor alpha (ER-alpha), the (D) estrogen receptor beta (ER-beta), and the (E) progesterone receptor (PR) in the epithelium of normal endometrium (normal EM), ovarian endometriosis (ovarian ES), peritoneal endometriosis (peritoneal ES) and deep-infiltrating endometriosis (deep ES), as well as (F-J) the same receptors in the stroma of the mentioned tissues. Stromal cells did not show cytoplasmic GPER expression in endometrium and endometriosis and hence no corresponding chart is represented in this figure. Significance (*) was considered if p ≤ 0.0083 in the pairwise analysis according to a Bonferroni correction (α’ = α/6). Highly significant values (p ≤ 0.0016) are marked with (**).

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