Regulation of EP2 and EP3 protein by different doses of estradiol. Results from manual scoring of EP2 and EP3 immunostaining in different uterine cell types when treated with different doses of estradiol (E2). Box and whisker plots representing the median value with 50% of all data falling within the box. The whiskers extend to the 5th and 95th percentiles. Bars with asterisks are significantly (P < 0.05) different from the control group (OvxC). LE- luminal epithelium, GE- glandular epithelium.