Electron micrographs of seminal vesicle of control and kisspeptin treated rats. a: A principal cell containing secretory granules, Golgi complex and endoplasmic reticulum. There were present some lipid droplets (LD), large dense core secretory granules (SG) and ribosomes (R). Twisted, irregular finger shaped microvilli were present at luminal border of principal cells. ×12,000. b: Seminal vesicle of animals treated with 10 pg kisspeptin. Number of secretary granules is lower. A mild dilatation of Golgi complex and endoplasmic reticulum is evident. ×5,000. c: Seminal vesicle of animals treated with 1 ng kisspeptin. Number of secretory granules was lower. Endoplasmic reticulum and Golgi apparatus were disorganized and dilated. Large vacuoles were evident. ×12,000. d: Seminal vesicle treated with 1 μg kisspeptin. Degeneration was more severe as compared to the other two treated groups. The alterations noticed were irregularity of nuclear shapes with intensive invagination of the envelope. No secretory granules were evident. ×15,000.