Mice age (weeks) | BMP conc. (ng) | Mice provided | Zygotes flushed | Zygotes fragmented (%) | Zygotes flushed/mouse | Zygotes cultured | Blastocyst (%) |
---|---|---|---|---|---|---|---|
6-11 (young control) | 0 (control) | 7 | 118 | 12 (10.2%) | 15.1 ± 4.7b | 106 | 38 (35.8%)c |
26-31 (aged control) | 0 (control) | 7 | 93 | 12 (12.9%) | 11.6 ± 4.6 | 81 | 13 (16.0%) |
0.01 | 8 | 105 | 16 (15.2%) | 11.1 ± 5.5 | 89 | 25 (28.1%)c | |
0.1 | 11 | 171 | 9 (5.3%)a | 14.7 ± 2.9b | 162 | 48 (29.6%)c | |
1 | 10 | 134 | 13 (9.7%) | 12.1 ± 4.5 | 121 | 14 (11.6%) | |
10 | 7 | 93 | 30 (32.3%) | 9 ± 5.6 | 63 | 2 (3.2%) |