Bone morphogenetic protein-15 in follicle fluid combined with age may differentiate between successful and unsuccessful poor ovarian responders

Table 1 Comparison of the characteristics and outcomes between women with different follicular BMP-15 levels

Parameter	Low BMP-15 (110 cycles)	High BMP-15 (97 cycles)	P value
BMP-15 level	0.95 (0.64–1.12)	1.35 (1.18–2.09)	<0.001^a
Age (yrs)	34 (24–39)	34 (25–39)	0.670^a
BMI (kg/m ² )	21.5 (15.8–33.8)	22.0 (15.2–28.0)	0.270 ^a
Basal FSH (IU/L)	7.46 (3.28–18.73)	8.0 (3.19–17.29)	0.137^a
No. of oocytes retrieved	3 (0–7)	3 (0–7)	0.396^a
ET cycle/started cycle	81.8%	84.5%	0.602^b
No. of embryos transferred	2 (0–3)	2 (0–3)	0.477^a
Implantation rate/embryo	15%	25.3%	0.023^b
Chemical pregnancy rate/ET cycle	23.3%	41.5%	0.011^b
Clinical pregnancy rate/ET cycle	21.1%	37.8%	0.016^b
Live born rate/ET cycle	15.6%	30.5%	0.019^b
Miscarriage rate	26.3%	19.4%	0.567^b

^a Values presented as medians (ranges) and compared by the Mann-Whitney-U test.
^b Values are compared with Chi-square test (likelihood ratio).