| |
Previous Poor response
|
Day 3 serum FSH > 12 UI/ml
|
|---|
|
Clomiphene (n=120)
|
High dose rFSH (n=118)
|
p
|
Clomiphene (n=25)
|
High dose rFSH (n=28)
|
p
|
|---|
|
Cancelled cycle
|
16 (3%)
|
18 (15%)
|
0.67
|
5 (20%)
|
3 (11%)
|
0.29
|
|
Number of oocytes retrieved
a
|
1.4 ± 1.1
|
2.8 ± 2.4
|
0.001
|
2.2 ± 0.8
|
2.8 ± 1.2
|
0.23
|
|
Fertilisation rate
b
|
88% (83/94)
|
69% (132/190)
|
0.001
|
50% (10/20)
|
67% (31/46)
|
0.27
|
|
Women performing embryo transfer
|
50 (42%)
|
61 (52%)
|
0.12
|
6 (24%)
|
18 (64%)
|
0.004
|
|
Number of embryos transferred
c
|
1.5 ± 0.7
|
1.8 ± 0.7
|
0.08
|
1.3 ± 0.5
|
1.6 ± 0.6
|
0.33
|
|
PR per started cycle
|
7% (8/120)
|
7% (8/118)
|
0.97
|
0% (0/25)
|
4% (1/28)
|
0.53
|
|
PR per embryo transfer
|
16% (8/50)
|
13% (8/61)
|
0.44
|
0% (0/6)
|
6% (1/18)
|
0.75
|
|
Embryos implanted (implantation rate)
|
12% (9/76)
|
9% (10/107)
|
0.63
|
0% (0/8)
|
7% (2/29)
|
1.00
|
|
DR per started cycle
|
4% (5/120)
|
5% (6/118)
|
0.74
|
0% (0/25)
|
4% (1/28)
|
0.53
|
|
DR per embryo transfer
|
10% (5/50)
|
10% (6/61)
|
1.00
|
0% (0/6)
|
6% (1/18)
|
0.75
|
- Data are expressed as mean ± SD or number (percentage) or percentage (ratio).
- a Refers to women who underwent oocyte retrieval.
- b Refers to all oocytes used.
- c Refers to women performing embryo transfer.
- PR: Clinical pregnancy rate. DR: Delivery Rate.
