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Table 2 IVF-ICSI cycle outcome in the two study groups

From: Clomiphene citrate versus high doses of gonadotropins for in vitrofertilisation in women with compromised ovarian reserve: a randomised controlled non-inferiority trial

Characteristics Clomiphene (n=145) High dose rFSH (n=146) p
Cancelled cycles 21 (14%) 21 (14%) 1.00
Number of follicles > 15 mm a 1.7 ± 1.1 2.8 ± 1.9 <0.001
Total number of follicles > 10 mm a 2.5 ± 1.4 4.1 ± 2.6 <0.001
Number of oocytes retrieved a 1.1 ± 1.1 2.0 ± 1.8 <0.001
    0 52 (42%) 29 (23%)  
    1-2 58 (47%) 57 (46%) <0.001
    ≥ 3 14 (11%) 39 (31%)  
Fertilisation rate b 75% (93/124) 70% (164/236) 0.33
Women performing Embryo Transfer 56 (39%) 79 (54%) 0.008
Number of embryos transferred c 1.5 ± 0.7 1.7 ± 0.7 0.06
    1 33 (59%) 33 (42%)  
    2 18 (32%) 35 (44%) 0.14
    3 5 (9%) 11 (14%)  
Number of pregnant women 8 9  
    PR per started cycle 5% (8/145) 6% (9/146) 1.00
    PR per retrieval 6% (8/124) 7% (9/125) 1.00
    PR per embryo transfer 14% (8/56) 11% (9/79) 0.81
Embryos implanted (implantation rate) 11% (9/84) 9% (12/136) 0.64
Number of live birth deliveries 5 7  
    DR per started cycle 3% (5/145) 5% (7/146) 0.77
    DR per retrieval 4% (5/124) 6% (7/125) 0.78
    DR per embryo transfer 9% (5/56) 9% (7/79) 1.00
  1. Data are expressed as mean ± SD or number (percentage) or median (interquartile range) or percentage (ratio).
  2. a Refers to women who underwent oocyte retrieval.
  3. b Refers to all oocytes used.
  4. c Refers to women performing embryo transfer.
  5. PR: Clinical pregnancy rate. DR: Delivery Rate.