Skip to main content
Figure 6 | Reproductive Biology and Endocrinology

Figure 6

From: Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down’s syndrome, preterm delivery and preeclampsia

Figure 6

Circulating hCG-sLHCGR in preeclampsia, preterm birth and fetal demise; a), the distribution of PAPP-A MoM and hCG-sLHCGR values (pmol/mL) from the prospective study (PS, n = 350) were plotted. Adverse pregnancies (preeclampsia, PET; preterm delivery, PD and FD, fetal demise) in each plot are shown as dark closed triangles whereas the controls are shown by closed grey triangles. The cut-off value for PAPP-A was ≤0.8 MoM, while those for hCG-sLHCGRwere set at ≤5 pmol/mL and ≥170 pmol/mL. All data were log-transformed and the regions within these cut-off values in each plot are highlighted by shaded boxes; b) and c), the relationship between high serum hCG-sLHCGR(>170 Pmol/mL) and free hCGbeta with control (n = 30), Down’s syndrome (DS, n = 7) and other pathological (n = 11) pregnancies are shown.

Back to article page