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Table 1 Clinical characteristics and laboratory values of study sample according to polycystic ovary syndrome (PCOS) and glucose tolerance status

From: The relationship between polycystic ovary syndrome, glucose tolerance status and serum preptin level

 

PCOS

Non-PCOS

 

NGT

IGT

NGT

IGT

No.

33

30

35

28

Age (y)

26.1 ± 2.4

27.2 ± 3.1

28.4 ± 3.1

29.4 ± 3.8

BMI (kg/m 2 )

21.8 ± 2.7

24.5 ± 3.1b

21.7 ± 3.2

20.6 ± 2.6

WHR

0.9 ± 0.6

0.9 ± 0.6

0.9 ± 0.7

0.9 ± 0.9

FSH (mIU/mL)

6.3 ± 1.6

5.5 ± 1.5a

6.3 ± 1.6

7.0 ± 3.9

LH (mIU/mL)

9.9 ± 3.9

8.6 ± 7.1

6.4 ± 2.0

4.3 ± 2.0d

Total T (ng/dL)

46.4 ± 11.7

47.5 ± 17.0

39.8 ± 10.0

36.0 ± 13.1

TG (mmol/L)

1.2 ± 0.5

1.9 ± 0.6b

1.3 ± 0.5

1.2 ± 0.6

TC (mmol/L)

4.4 ± 0.6

4.8 ± 0.6a

4.2 ± 0.8

4.2 ± 0.8

HDL-C (mmol/L)

1.6 ± 0.3

1.2 ± 0.2b

1.50 ± 0.3

1.4 ± 0.5

LDL-C (mmol/L)

2.4 ± 0.5

2.7 ± 0.2b

2.6 ± 0.4

2.3 ± 0.5c

SBP (mmHg)

113.8 ± 14.9

125.9 ± 13.6b

123.7 ± 13.3

112.2 ± 15.1d

DBP (mmHg)

77.1 ± 9.8

82.9 ± 11.4a

76.9 ± 8.0

78.0 ± 10.7

FBG (mmol/L)

5.5 ± 0.5

6.5 ± 0.8b

5.3 ± 0.4

5.8 ± 0.7d

2h_OGTT (mmol/L)

7.0 ± 0.5

9.2 ± 0.8b

7.1 ± 0.5

9.8 ± 1.0d

FIns (mU/L)

12.0 ± 3.7

13.6 ± 4.8

10.3 ± 1.5

13.6 ± 5.3d

HbA 1 c (%)

5.3 ± 0.4

6.0 ± 0.9b

5.5 ± 0.2

6.0 ± 0.7d

HOMA-IR

2.9 ± 0.9

3.9 ± 1.5b

2.4 ± 0.4

3.5 ± 1.4d

Preptin (pg/mL)

413.7 ± 106.6

522.1 ± 135.1b

406.1 ± 79.9

466.4 ± 121.1c

  1. Data presented as mean ± SD.PCOS polycystic ovary syndrome, NGT normal glucose tolerance, IGT impaired glucose tolerance, BMI body mass index, WHR waist-to-hip ratio, FSH follicle-stimulating hormone, LH luteinizing hormone, total T total testerone, TG triglyceride, TC total cholesterol, HDL high-density lipoprotein, LDL low-density lipoprotein; SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose; 2h_OGTT 2-h blood glucose after glucose overload, FIns fasting insulin, HbA1c glycosylated haemoglobin, HOMA-IR homeostasis model assessment-insulin resistance index, HOMA-IS homeostasis model assessment-β-cell insulin secretion index
  2. a P < 0.05 PCOS patients with IGT compared with PCOS patients with NGT
  3. b P < 0.01 PCOS patients with IGT compared with PCOS patients with NGT
  4. c P < 0.05 Non-PCOS patients with IGT compared with non-PCOS patients with NGT
  5. d P < 0.01 Non-PCOS patients with IGT compared with non-PCOS patients with NGT