Figure 2

Concentration – response relationships of DEA/NO-induced relaxation before and after pretreatment with blockers of Ca²⁺-sensitive K⁺ channels: (A) DEA/NO alone (n = 10), DEA/NO after preincubation with 10 nM scyllatoxin (n = 5), or 10 nM apamin (n = 10); (B) DEA/NO in the absence and presence of 100 nM CTX (n = 10). Each point represents the mean ± SEM and * indicates effects significantly different from those observed in absence of the blockers (ANOVA). The spontaneous contractile activity was treated as a control.