Figure 3

Effects of ICI 182, 780 on the expression of ERβ in the rat efferent ductules. In the control rats (A, B, E, F), ERβ was expressed in the nuclei of the efferent ductules epithelial and some stromal cells (*). An intermittent staining was also detected in the peritubular cells (arrow); (c) ciliated cells. Insert in A represents the negative control. The ERβ staining was stronger in the efferent ductules proximal tubules and initial segment of the epididymis when compared to the efferent ductules distal tubules. There were no detectable changes in the efferent ductules ERβ expression after ICI treatment (C, D, G, H). EP = epididymis. Bar in A = 50 μm.