Skip to main content

Table 2 Phenotypic differences of NFH-OSE and FH-OSE in culture

From: Ovarian surface epithelium: family history and early events in ovarian cancer

Response to environmental signals greater lesser
Growth potential greater lesser
Telomeric length longer shorter
Metaplastic colonies in primary culture rare frequent
Expression of   
   CA125 rare prominent
   E-cadherin rare prominent
   High molecular weight keratin less more
   Collagen III more less
Coexpression of HGF and Met receptor rare frequent
Signaling pathways (such as PI3K) non-activated activated