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Table 1 Histopathologic alterations of ovaries from women with family history of ovarian cancer

From: Ovarian surface epithelium: family history and early events in ovarian cancer

  Present Absent
Histologic   
Metaplasia of surface epithelium [13] [1417]
   Papillomatosis   
   Stratification   
   Epithelial inclusion cysts   
   Invaginations   
Stromal hyperplasia [13] [14, 15]
Cytologic   
Nuclei of the surface epithelium [14, 16, 18]  
   Larger nuclei   
Irregular contours   
Heterogenous dense chromatin   
Molecular   
Increased expression of p53, c-erbB and Ki-67   [15, 19]