Uterus of Chalcides chalcides at the pre-ovulatory vitellogenic stage. A (negative control: without primary antibody). The uterine mucosa is thrown up into many long folds. Basal to the luminal epithelium (E) of low columnar cells, a lamina propria with numerous blood vessels (V) and the myometrium with outer longitudinal (L) and inner circular (C) layers are evident. B A strong immunoreactivity for IL-1α in the connective tissue and glandular cells of the lamina propria (arrows), and a weak reaction in the myometrium (*), where only a few epithelial cells are positive (arrowheads). C. Widespread immunoreactivity for IL-1β is seen in the luminal epithelium and in the myometrium. D. Immunoreactivity for IL-1R tI in the luminal epithelium (arrows), myometrium and cytoplasm of glandular cells (*). Bars = 25 μm.