Figure 2
From: Ovarian responses to undernutrition in pregnant ewes, USA
Fluorescence intensity scores of oogonia/oocytes: A, fetal 8-oxoguanine; B, fetal p53; C, fetal Bcl-2; D, fetal polymerase β; E, fetal apoptosis (DNA fragmentation); F, maternal p53 (fetal control, n = 4; fetal restricted, n = 5; maternal control, n = 7; maternal restricted, n = 6). Asterisks indicate pairwise increases (P < 0.01). Values for negative controls (not subtracted from the data shown) were < 45. Representative photomicrographs of p53-immunostained oogonia of control (left panel) and restricted (center panel) fetuses are shown in the inset (note the contrast in magnitudes of nuclear fluorescence); a negative preabsorption control cell (restricted fetus) is shown in the right panel.