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Table 1 Putative transcription factor binding sites

From: SPAM1 (PH-20) protein and mRNA expression in the epididymides of humans and macaques: utilizing laser microdissection/RT-PCR

Transcription Factor Binding Sequence

Binding Site Location (-bp)

ARE

661, 763

GATA family

92, 125, 313, 397

PEA3

696, 741, 900, 1063

SRY

18, 155, 661

CRE

207

  1. In silico analysis of the human SPAM1 5' flanking region detected several putative transcription factor binding sites associated with epididymal expression. Androgen responsive elements (ARE), GATA-family sequences, and PEA3 sequences are markers for epididymal expression [43]. SRY and CRE are markers for testicular expression.