Figure 1
From: Relaxin receptors and nitric oxide synthases: search for the missing link
Putative interactions between relaxin receptor signaling and intrinsic NO pathway. AC: adenylate cyclase Akt: protein kinase B Gs: Gs proteins IκB inhibitor subunit of nuclear factor kappa-B LGR7-8: leucine-rich repeat-containing G protein-coupled receptors 7 and 8 NF-κB nuclear factor kappa-B NO: nitric oxide NOS II: inducible NO synthase NOS III: constitutive NO synthase PI3-K: phosphoinositide 3-kinase PKA: protein kinase A RLX: relaxin