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Table 2 Number (×106) of germ cells undergoing apoptosis in age-matched control (WT) and in transgenic (TG) mice homozygous to rat ABP.

From: Dynamics of testicular germ cell apoptosis in normal mice and transgenic mice overexpressing rat androgen-binding protein

  Spermatogonia and Secondary spermatocytes (2C) Spermatogonia synthesizing DNA (S-Phase) Primary spermatocytes (4C) Spermatids (1C)
Days WT TG WT TG WT TG WT TG
7 days 0.18 ± 0.04 0.23 ± 0.09 0.065 ± 0.026 0.065 ± 0.046 0.23 ± 0.061 0.26 ± 0.15   
10 days 0.77 ± 0.16 0.73 ± 0.17 0.270 ± 0.156 0.266 ± 0.166 0.84 ± 0.072 0.75 ± 0.178   
14 days 5.88 ± 2.12 6.49 ± 1.52 0.832 ± 0.41 1.172 ± 0.61 9.08 ± 0.70 12.04 ± 2.81   
21 days 11.21 ± 3.38 19.48 ± 3.16 a 1.39 ± 0.64 4.03 ± 0.42 c 10.31 ± 3.61 28.87 ± 4.31 c 1.88 ± 1.58 2.58 ± 0.56
30 days 31.24 ± 6.76 42.32 ± 1.95 b 5.91 ± 1.79 12.28 ± 5.12 a 18.48 ± 4.21 29.78 ± 5.08b 86.10 ± 19.51 103.42 ± 8.65
60 days 16.43 ± 8.61 26.94 ± 4.75 a 3.92 ± 1.85 11.35 ± 4.85 a 23.38 ± 8.38 28.08 ± 8.04 42.36 ± 12.64 50.01 ± 12.54
90 days 31.64 ± 9.54 16.44 ± 5.82 a 11.16 ± 1.95 7.34 ± 1.29 a 36.14 ± 11.0 20.69 ± 5.78 a 72.66 ± 13.00 47.49 ± 16.16 a
120 days 43.47 ± 9.30 35.64 ± 5.78 28.33 ± 6.51 23.08 ± 4.67 41.46 ± 9.94 29.72 ± 1.67 41.16 ± 5.75 29.84 ± 7.02a
180 days 48.72 ± 10.71 34.30 ± 5.18 25.31 ± 8.59 15.95 ± 2.76 53.70 ± 9.37 43.01 ± 15.71 57.05 ± 12.14 37.70 ± 4.88 a
240 days 67.24 ± 13.04 43.44 ± 4.51 a 26.29 ± 4.34 12.03 ± 1.11 a 56.68 ± 8.59 36.16 ± 5.15 c 52.03 ± 11.06 32.08 ± 6.66 c
360 days 58.62 ± 40.10 26.10 ± 6.56 15.57 ± 3.99 7.61 ± 4.61 a 34.03 ± 13.0 17.70 ± 1.24c 95.74 ± 27.93 58.76 ± 8.11a
  1. Unpaired 't' test was used; Values are Mean ± SD of 5 estimations; a p < 0.05; b p < 0.01; c p < 0.001 Statistical comparisons are between wild type control and TG mice at each individual age.