Table 1 -
From: Differentiation of adult-type Leydig cells occurs in gonadotrophin-deficient mice
Gene | Expression per testis (relative to Luciferase × 103) | GnRH-null relative to adult normal (corrected for cell number)2 | ||
|---|---|---|---|---|
Adult GnRH-null | Adult normal | Neonatal normal1 | ||
P450scc | 0.23 ± 0.04 | 242 ± 35 | 2.2 ± 0.5 | 0.95% |
P450c17 | 15.3 ± 1.8 | 3453 ± 1042 | 13.5 ± 3.5 | 4.4% |
GST5-5 | 60.6 ± 5.6 | 677 ± 91 | 76 ± 15 | 89.5% |
RLF | 19.2 ± 2.1 | 2490 ± 611 | 5.3 ± 1.3 | 7.7% |
3βHSD I | 7.5 ± 1.7 | 51 ± 10 | 4.6 ± 1.8 | 147.0% |
Renin | 0.027 ± 0.012 | 21.4 ± 3.5 | 5.8 ± 0.9 | 1.3% |
EH | 18.5 ± 1.6 | 996 ± 112 | 8.0 ± 1.6 | 18.5% |
StAR | 2.08 ± 0.2 | 177 ± 30 | 4.0 ± 1.1 | 11.7% |
3βHSD VI* | 0.014 ± 0.005 | 124 ± 15 | ND3 | 0.11% |
PGD-synthetase* | 0.26 ± 0.06 | 843 ± 43 | 2.5 ± 1.1 | 0.31% |
EST* | 0.014 ± 0.009 | 9.0 ± 2.4 | ND3 | 1.5% |
17βHSD III* | 2.39 ± 0.21 | 1644 ± 192 | 140 ± 7 | 1.45% |