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Figure 1 | Reproductive Biology and Endocrinology

Figure 1

From: Lysophosphatidic acid, LPA: a bad boy becomes good

Figure 1

Secretory ecto-phospholipases produce biologically active lipid, lysophosphatidic acid (LPA). LPA should be released into extracellular fluid to signal through its specific G-protein coupled receptor (LP-R) [7]. Secretory ecto-enzymes like Lysophospholipase D (LPLD) or secretory-type Phospholipase A2 (sPLA2) act on phospholipd substrates available in extracellular leaflets of the plasma membrane (and can supply LPA directly to its receptors).

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