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Figure 7 | Reproductive Biology and Endocrinology

Figure 7

From: Placental expression of estrogen receptor beta and its hormone binding variant – comparison with estrogen receptor alpha and a role for estrogen receptors in asymmetric division and differentiation of estrogen-dependent cells

Figure 7

Immunoreactivity of the E12 and F12 antibodies recognizing ERβ hormone binding domain in CV and placental membranes. [A] The E12 antibody shows nuclear-specific localization of ERβ in villous ST (full arrowheads). [B] The F12 antibody shows nuclear-specific localization of ERβ in villous ST and adjacent CT cells merging with ST (white arrowheads). [C] Control for panels [A] and [B]. [D] In placental membranes, the F12 (and E12 – data not shown) antibodies showed nuclear-specific localization of ERβ in amniotic epithelium (full arrowhead), fibroblasts (arrow) and EVT (white arrowheads) – compare with control in [E]. Bar in [B] for [A–C]; bar in [E] for [D and E].

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