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Table 2 IL-11Rα immunostaining in cynomolgus and rhesus monkey implantation sites, and human first trimester decidua and placenta.

From: IL-11 and IL-11Rα immunolocalisation at primate implantation sites supports a role for IL-11 in placentation and fetal development

 

Implantation sites

 

Cynomolgus

Rhesus

Human

Day of gestation

12–14

17

27–49

74–150

24–35

8–9 weeks

Trophoblast

      

Villi – cyto

-

-/+

-

-

++/+

+++

   - syncytio

-

-/+

-

-

++/+

+++

   - mesenchyme

-/+

-

++/+

+

+

+++

Shell

+

+

-/+

+

-

N/A

Cyto- invading artery

+

+/++

-/+

-

-

N/A

Mother

      

Decidua

++

+++

+++

+++

+++

+++

VSM

-/+

+++

+++

+

+

++

Endothelial

-/+

+++

+/++

+

-

-/+

Glands

-

-/+

-/+

-

-/+

+

Perivascular

-

++/+

++/+

+

+++

++

Epithelial plaques

+/++

+

N/A

N/A

N/A

N/A

  1. Relative staining intensities are represented as: – (no staining), + (low), ++ (moderate) and +++ (high). Trophoblast cellular compartments include: Chorionic villi (villi), villous cytotrophoblast (cyto), villous syncytiotrophoblast (syncytio), villous stromal mesenchyme (mesenchyme), cytotrophoblast shell (shell), cytotrophoblast invading spiral artery (cyto-invading artery). Maternal cellular compartments include: decidua, vascular smooth muscle cells (VSM), endothelial cells, glands, perivascular cells and epithelial plaque.