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Table 1 Effect of p-nonylphenol (NP; 50 μg and 500 μg) and resveratrol (RES; 3 mg) on different body parameters in male outbred CD1 mice. The control and experimental groups of the same sex were killed at identical times. The body weights and organ weights were taken individually. The ratio between the organ weight and body weight represents the relative organ weight. (* P < 0.05, ** P < 0.01).

From: Effects of p-nonylphenol and resveratrol on body and organ weight and in vivo fertility of outbred CD-1 mice

 

P

F1

Variable

Control

NP 50

NP 500

RES

Control

NP 50

NP 500

RES

Body weight (g)

39.42 ± 1.60

40.26 ± 0.52

42.83 ± 1.80

36.05 ± 2.52

36.88 ± 0.32

36.73 ± 0.95

42.32 ± 1.17**

36.65 ± 1.67

Testis weight (mg)

121.4 ± 6.1

99.3 ± 6.2**

126.5 ± 3.3

118.7 ± 5.1

112.5 ± 2.2

102.5 ± 2.6**

107.4 ± 8.3

114.5 ± 6.8

Testis weight/Body weight

3.09 ± 0.09

2.46 ± 0.12**

2.97 ± 0.10

3.36 ± 0.21

3.05 ± 0.07

2.87 ± 0.11

2.53 ± 0.16*

3.11 ± 0.07

Epididymis weight (mg)

56.1 ± 1.0

58.3 ± 2.1

69.2 ± 2.0**

53.8 ± 3.0

53.4 ± 3.1

49.0 ± 0.9

58.2 ± 1.5

56.9 ± 7.2

Epididymis weight/Body weight

1.44 ± 0.09

1.45 ± 0.03

1.63 ± 0.07*

1.51 ± 0.06

1.45 ± 0.09

1.34 ± 0.04

1.33 ± 0.05

1.55 ± 0.04

Prostate weight (mg)

140.5 ± 15.5

126.7 ± 6.2

142.98 ± 16.3

125.6 ± 26.4

149.2 ± 7.8

130.5 ± 5.6**

150.4 ± 3.5

149.2 ± 13.5

Prostate weight/Body weight

3.58 ± 0.41

3.15 ± 0.15

3.38 ± 0.46

3.60 ± 0.66

4.05 ± 0.21

3.55 ± 0.11*

3.57 ± 0.08

4.07 ± 0.28

Seminal vesicle weight (mg)

193.1 ± 9.5

184.1 ± 6.8

205.6 ± 16.6

156.2 ± 14.3**

154.5 ± 0.3

142.3 ± 7.9

226.6 ± 15.3**

126.9 ± 12.3*

Sem.ves.weight/Body weight

4.93 ± 0.28

4.57 ± 0.18

4.67 ± 0.26

4.34 ± 0.16*

4.19 ± 0.03

3.86 ± 0.19

4.38 ± 0.44

3.47 ± 0.24

Liver weight (mg)

2580 ± 152

2816 ± 75

2805 ± 103

2048 ± 162*

2749 ± 30

2397 ± 35**

2656 ± 123

2500 ± 191

Liver weight/Body weight

65.45 ± 3.86

69.95 ± 1.86

65.49 ± 2.40

56.81 ± 4.49

74.54 ± 0.76

65.26 ± 0.95**

62.76 ± 2.91**

68.21 ± 5.21

Kidney weight (mg)

404.3 ± 15.0

354.9 ± 7.8*

415.7 ± 10.0

355.7 ± 39.3

355.8 ± 2.5

396.9 ± 13.1**

406.3 ± 5.4**

321.6 ± 59.3*

Kidney weight/Body weight

10.27 ± 0.33

8.83 ± 0.32**

9.52 ± 0.46

9.78 ± 0.52

9.65 ± 0.15

10.83 ± 0.48

9.65 ± 0.43

8.73 ± 0.21

Spleen weight (mg)

99.4 ± 3.6

101.6 ± 5.7

108.8 ± 6.7

82.2 ± 7.1*

105.3 ± 13.2

93.68 ± 5.7

110.6 ± 12.4

111.7 ± 12.7

Spleen weight/Body weight

2.53 ± 0.11

2.52 ± 0.13

2.54 ± 0.08

2.31 ± 0.21

2.86 ± 0.42

2.54 ± 0.11

2.60 ± 0.19

3.01 ± 0.28