| P | F1 | ||||||
---|---|---|---|---|---|---|---|---|
Variable | Control | NP 50 | NP 500 | RES | Control | NP 50 | NP 500 | RES |
Body weight (g) | 39.42 ± 1.60 | 40.26 ± 0.52 | 42.83 ± 1.80 | 36.05 ± 2.52 | 36.88 ± 0.32 | 36.73 ± 0.95 | 42.32 ± 1.17** | 36.65 ± 1.67 |
Testis weight (mg) | 121.4 ± 6.1 | 99.3 ± 6.2** | 126.5 ± 3.3 | 118.7 ± 5.1 | 112.5 ± 2.2 | 102.5 ± 2.6** | 107.4 ± 8.3 | 114.5 ± 6.8 |
Testis weight/Body weight | 3.09 ± 0.09 | 2.46 ± 0.12** | 2.97 ± 0.10 | 3.36 ± 0.21 | 3.05 ± 0.07 | 2.87 ± 0.11 | 2.53 ± 0.16* | 3.11 ± 0.07 |
Epididymis weight (mg) | 56.1 ± 1.0 | 58.3 ± 2.1 | 69.2 ± 2.0** | 53.8 ± 3.0 | 53.4 ± 3.1 | 49.0 ± 0.9 | 58.2 ± 1.5 | 56.9 ± 7.2 |
Epididymis weight/Body weight | 1.44 ± 0.09 | 1.45 ± 0.03 | 1.63 ± 0.07* | 1.51 ± 0.06 | 1.45 ± 0.09 | 1.34 ± 0.04 | 1.33 ± 0.05 | 1.55 ± 0.04 |
Prostate weight (mg) | 140.5 ± 15.5 | 126.7 ± 6.2 | 142.98 ± 16.3 | 125.6 ± 26.4 | 149.2 ± 7.8 | 130.5 ± 5.6** | 150.4 ± 3.5 | 149.2 ± 13.5 |
Prostate weight/Body weight | 3.58 ± 0.41 | 3.15 ± 0.15 | 3.38 ± 0.46 | 3.60 ± 0.66 | 4.05 ± 0.21 | 3.55 ± 0.11* | 3.57 ± 0.08 | 4.07 ± 0.28 |
Seminal vesicle weight (mg) | 193.1 ± 9.5 | 184.1 ± 6.8 | 205.6 ± 16.6 | 156.2 ± 14.3** | 154.5 ± 0.3 | 142.3 ± 7.9 | 226.6 ± 15.3** | 126.9 ± 12.3* |
Sem.ves.weight/Body weight | 4.93 ± 0.28 | 4.57 ± 0.18 | 4.67 ± 0.26 | 4.34 ± 0.16* | 4.19 ± 0.03 | 3.86 ± 0.19 | 4.38 ± 0.44 | 3.47 ± 0.24 |
Liver weight (mg) | 2580 ± 152 | 2816 ± 75 | 2805 ± 103 | 2048 ± 162* | 2749 ± 30 | 2397 ± 35** | 2656 ± 123 | 2500 ± 191 |
Liver weight/Body weight | 65.45 ± 3.86 | 69.95 ± 1.86 | 65.49 ± 2.40 | 56.81 ± 4.49 | 74.54 ± 0.76 | 65.26 ± 0.95** | 62.76 ± 2.91** | 68.21 ± 5.21 |
Kidney weight (mg) | 404.3 ± 15.0 | 354.9 ± 7.8* | 415.7 ± 10.0 | 355.7 ± 39.3 | 355.8 ± 2.5 | 396.9 ± 13.1** | 406.3 ± 5.4** | 321.6 ± 59.3* |
Kidney weight/Body weight | 10.27 ± 0.33 | 8.83 ± 0.32** | 9.52 ± 0.46 | 9.78 ± 0.52 | 9.65 ± 0.15 | 10.83 ± 0.48 | 9.65 ± 0.43 | 8.73 ± 0.21 |
Spleen weight (mg) | 99.4 ± 3.6 | 101.6 ± 5.7 | 108.8 ± 6.7 | 82.2 ± 7.1* | 105.3 ± 13.2 | 93.68 ± 5.7 | 110.6 ± 12.4 | 111.7 ± 12.7 |
Spleen weight/Body weight | 2.53 ± 0.11 | 2.52 ± 0.13 | 2.54 ± 0.08 | 2.31 ± 0.21 | 2.86 ± 0.42 | 2.54 ± 0.11 | 2.60 ± 0.19 | 3.01 ± 0.28 |