Skip to main content

Table 1 Oolemmal surface-labeled Chaperone/HSPs Identified by TMS. List of putative oolemmal proteins identified by 2D electrophoresis and TMS, with predicted molecular weight and isoelectric point, genbank accession number, expression profile with associated references and presence or absence of ER-retention sequence (KDEL).

From: Oolemmal proteomics – identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane

Protein MW pI Acc. # Hsp or chaperone Previously described on cell surface Previously described in oocyte ER-retention motif
HSP 70 70.0 5.46 P17879 HSP [2224] [3235, 3840] -
HSP 90 (HSP 86) 84.7 4.93 P07901 HSP [23] [36] -
GRP 94 (gp96) 92.5 4.74 P08113 HSP [16, 18, 21, 30] - +KDEL
GRP 78 (BiP) 72.4 5.07 P20029 HSP [16, 28, 30, 31] - +KDEL
ORP 150 11.1 5.11 AAB05672 HSP - - + KNDEL
Calreticulin 48.0 4.33 P14211 Chaperone [16, 25, 26, 28] [43, 44] +KDEL
Calnexin 6.50 4.48 AAA62450 Chaperone [16, 17, 1922] - + KPRRE
PDI 57.1 4.80 P09103 Chaperone [2729] [45] +KDEL