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Table 1 Oolemmal surface-labeled Chaperone/HSPs Identified by TMS. List of putative oolemmal proteins identified by 2D electrophoresis and TMS, with predicted molecular weight and isoelectric point, genbank accession number, expression profile with associated references and presence or absence of ER-retention sequence (KDEL).

From: Oolemmal proteomics – identification of highly abundant heat shock proteins and molecular chaperones in the mature mouse egg and their localization on the plasma membrane

Protein

MW

pI

Acc. #

Hsp or chaperone

Previously described on cell surface

Previously described in oocyte

ER-retention motif

HSP 70

70.0

5.46

P17879

HSP

[2224]

[3235, 3840]

-

HSP 90 (HSP 86)

84.7

4.93

P07901

HSP

[23]

[36]

-

GRP 94 (gp96)

92.5

4.74

P08113

HSP

[16, 18, 21, 30]

-

+KDEL

GRP 78 (BiP)

72.4

5.07

P20029

HSP

[16, 28, 30, 31]

-

+KDEL

ORP 150

11.1

5.11

AAB05672

HSP

-

-

+ KNDEL

Calreticulin

48.0

4.33

P14211

Chaperone

[16, 25, 26, 28]

[43, 44]

+KDEL

Calnexin

6.50

4.48

AAA62450

Chaperone

[16, 17, 1922]

-

+ KPRRE

PDI

57.1

4.80

P09103

Chaperone

[2729]

[45]

+KDEL