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Table 1 Stimulation of testosterone secretion by hCG in control and testosterone-pretreated Leydig cellsa.

From: Expression of somatostatin receptor type-2 (sst2A) in immature porcine Leydig cells and a possible role in the local control of testosterone secretion

 

Secreted tesosterone (nM)

hCG (ng/ml)

control

pretreated

0

0.060 ± 0.0001b

0.250 ± 0.013*

0.065

0.200 ± 0.003d

0.400 ± 0.004*

0.125

0.280 ± 0.034c

0.450 ± 0.024*

0.250

0.330 ± 0.028d

0.630 ± 0.026c,*

0.500

0.290 ± 0.030d

0.730 ± 0.052c,*

1

0.370 ± 0.035d

0.630 ± 0.034c,*

2

0.500 ± 0.052e

0.960 ± 0.052d*

4

0.460 ± 0.043e

0.890 ± 0.061d*

  1. a pretreatment conditions are given in "Materials and Methods". bdata are expressed as mean ± SEM. c,d,etestosterone secretion significantly (c:p < 0.05; d:p < 0.01; e:p < 0.001) higher in the presence of hCG than in its absence in either control- or testosterone-pretreated cells *testosterone secretion significantly (p < 0.01) higher for the same hCG concentration in testosterone-pretreated than control cells.
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Reproductive Biology and Endocrinology

ISSN: 1477-7827

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