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Figure 2 | Reproductive Biology and Endocrinology

Figure 2

From: Immunoexpression of the relaxin receptor LGR7 in breast and uterine tissues of humans and primates

Figure 2

Immunostaining of sections of uterus (endometrium) from a single female cynomolgus macaque in the secretory phase of the estrous cycle. Specific LGR7 immunostaining is consistently observed in endometrial stromal cells for all three LGR7 epitopes (A, L7-1; D, L7-2; G, L7-3), which is not observed when applying the preimmune sera at the same concentration (B, E, H). Variable immunostaining is observed also in the glandular epithelial cells (A, D, G; arrowheads, which, however, is completely attenuated upon preincubating the diluted primary antisera with an excess of the hapten, KLH (C, F, I). Sera from only one animal was chosen for each epitope (L7-1, R1; L7-2, R2; L7-3, R3). A second monkey, also in the secretory phase, was also analysed in parallel with identical results (not shown). Scale bar = 50 μm.

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