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Table 3 Management of Women with VTE

From: Thrombophilia and pregnancy

Category

Patients

Recommendation

Very high risk for VTE

Previous VTE on anticoagulants; VTE in current pregnancy; Antithrombin deficiency

LMW heparin (Enoxaparin) mg/kg Twice day OR heparin adjusted dose with confirmation of pregnancy

High risk for VTE

Previuos VTE; Protein C, S deficiency plus family history of VTE;homozygote FV or prothrombin mutation; combined thrombophilia

LMW heparin (Enoxaparin) 40 mg/day until 6–12 weeks postpartum Or fixed dose heparin

Moderate risk for VTE

Heterozygote FV or prothrombin mutation, PS deficiency, and family history VTE

Postpartum anticoagulation LMW heparin (Enoxaparin) 40 mg/day

Relatively low risk for VTE

Heterozygote FV or prothrombin mutation; no personal or family history VTE

Monitor for additional risks for VTE