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Table 3 Management of Women with VTE

From: Thrombophilia and pregnancy

Category Patients Recommendation
Very high risk for VTE Previous VTE on anticoagulants; VTE in current pregnancy; Antithrombin deficiency LMW heparin (Enoxaparin) mg/kg Twice day OR heparin adjusted dose with confirmation of pregnancy
High risk for VTE Previuos VTE; Protein C, S deficiency plus family history of VTE;homozygote FV or prothrombin mutation; combined thrombophilia LMW heparin (Enoxaparin) 40 mg/day until 6–12 weeks postpartum Or fixed dose heparin
Moderate risk for VTE Heterozygote FV or prothrombin mutation, PS deficiency, and family history VTE Postpartum anticoagulation LMW heparin (Enoxaparin) 40 mg/day
Relatively low risk for VTE Heterozygote FV or prothrombin mutation; no personal or family history VTE Monitor for additional risks for VTE